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Ently used for encapsulating and successfully [39] delivering a variety of anticancerEntly used for encapsulating and successfully [39] delivering a variety of anticancer drugs (reviewed in ). Problems of stability, cytotoxicity and conservation may represent constrains that require further optimized [42] formulations .POLYMERIC NANOPARTICLESPolymer-based nanoparticle delivery systems (polym
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R-activated receptor alpha (PPARa) regulates CYP4A [11-14]. SXR and CAR are closely related nuclear receptors (NR1I) that are activated by a wide range of compounds including several clinically used drugs [15]. AhR is a major xenobioticsensing receptor that is activated by environmental pollutants such as dioxin and PAHs including benzo[a]pyrene (BaP) [16,17]. AhR and its dimerization partner AhR
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R-activated receptor alpha (PPARa) regulates CYP4A [11-14]. SXR and CAR are closely related nuclear receptors (NR1I) that are activated by a wide range of compounds including several clinically used drugs [15]. AhR is a major xenobioticsensing receptor that is activated by environmental pollutants such as dioxin and PAHs including benzo[a]pyrene (BaP) [16,17]. AhR and its dimerization partner AhR
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Th Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cellsTh Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cells able to produce IFN- . Moreover, a moderate neutralizing antibody response was found in rabbits immunized with an E2 scaffold displaying a peptide [67] mimotope of the HIV-1 gp120 bridging sheet . Furthermore, E2 multimeric scaffolds displ
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Th Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cellsTh Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cells able to produce IFN- . Moreover, a moderate neutralizing antibody response was found in rabbits immunized with an E2 scaffold displaying a peptide [67] mimotope of the HIV-1 gp120 bridging sheet . Furthermore, E2 multimeric scaffolds displ